Ibuprofen is the most effective painkiller to use during a medical abortion and does not have any influence on the abortion. 27,28, 29 Ibuprofen can be taken after or before using the misoprostol.  Acetaminophen (paracetamol) or NSAIDs such as naproxine can also be used but are less effective than ibuprofen.

A hot-water bottle or heating pad, sitting or lying comfortably, listening to the music, a good book or movie, and support from friends and family can all help to relieve pain. 15