Other side effects

Nausea and vomiting are frequent pregnancy-related symptoms but they may become worse with the use of misoprostol. Fever below 38º for a few hours, chills, nausea, vomiting, diarrhea, headache and flu-like symptoms are all side effects of misoprostol. They usually occur within the hour following administration and last for 1 to 2 hours and should resolve within 6 hours of using the misoprostol. ^15,31

If a woman feels ill, has intense abdominal pain, nausea, vomiting and/or diarrhea, or has a fever lasting more than 24 hours after using misoprostol she should see the doctor.